An increased gradient of MS is observed in northern compared with southern regions of the northern hemisphere, postulated to be due to genetic, environmental, cultural and behavioural differences. MS-related changes to these nerve pathways can directly or indirectly impair sexual functioning. Recommended for You ARTICLE What Are the 4 Types of MS? J Neurol Neurosurg Psychiatry. The FPA offers information, services and support on family planning and contraception - www. They had mean EDSS score of 2.
SNPs to pathways to pathogenesis. Current Neurology and Neuroscience Reports. If migration takes place after age 15, however, the person retains the risk of their home country. Studies of adopted children who develop MS illustrate genetic and not environmental causes for aggregation of MS in families [ Dyment et al.
Multiple sclerosis signs and symptoms may differ greatly from person to person and over the course of the disease depending on the location of affected nerve fibers. However, treatments can help speed recovery from attacks, modify the course of the disease and manage symptoms. Variation in drug responses between patients with MS might also be due to genetic differences between individuals [ Comabella and Vandenbroeck, ]. This study increased the list of MS-associated loci to 52 and identified lists of additional others as interesting candidate genes.
Of course, one cannot exclude a selection bias, in that mildly affected patients are more positive towards having children than those with early disability. Rezvani Roya, Mehrafarin Building, Merabad Street, Isfahan, Iran. Introduction Multiple sclerosis MS is a chronic inflammatory disease of the central nervous system CNS that is prevalent in the northern hemisphere 0. During the postpartum period there is a decrease in pregnancy hormones. Therefore, our final sample comprised women. Few data on accidental exposures to fingolimod and teriflunomide have been reported to date, but because of the potential risk of foetal toxicity based on animal studies, use of effective contraception is mandatory.
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